Last major update: November 2008 - next update November 2009
Revised: 22 September 2009
Author: Nat Pernick, M.D., PathologyOutlines.com, Inc.
Copyright: (c) 2002-2009, PathologyOutlines.com, Inc.
Features to report
Specimen type / procedure:
● Tumor location
● Histologic subtype
● Margin of excision (distance from tumor) - lateral and deep
● Angiolymphatic invasion (if present)
Mandatory features used for pathologic staging:
● Tumor thickness (Breslow)
● Tumor ulceration
● Number of nodes examined, number with melanoma (if available)
Features used in some protocols for treatment choice:
● Tumor depth (Clark’s levels)
● Tumor size
● Tumor mitotic rate
● Precursor lesion
● Host lymphocytic response (absent, present non-brisk, brisk)
● Mitotic index (reported per mm2)
● Characteristics of radial growth phase and vertical growth phase
● Synoptic reports are more complete than non-synoptic reports; recommendations include free text option, tailoring to each institution and regular updates (Histopathology 2008;52:130)
● Example - Michigan Cancer Consortium
End of Skin-Melanocytic Tumors > Melanoma – features to report
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