Skin - Nonmelanocytic tumors
Lymphoma and related disorders
Acute lymphoblastic lymphoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 14 October 2016, last major update June 2012

Copyright: (c) 2001-2016,, Inc.

PubMed search: acute lymphoblastic lymphoma [title]

Cite this page: Acute lymphoblastic lymphoma. website. Accessed October 22nd, 2016.
Definition / General
  • Most common cutaneous lymphoma in children; rare in adults
  • Aggressive behavior
  • Either B cell (CD19+, CD20+, CD79a+), T cell (surface CD3+) or non B, non T (negative for B cell markers and CD3)
  • T cell subtypes have best prognosis
  • Non B, non T include:
    • (a) CD7+ stem cell lymphoma (CD7+, CD4-, CD56-, CD33 variable)
    • (b) blastic NK lymphoma (CD56+, CD4-, CD33-, CD123-, CD7 variable)
    • (c) myeloid / NK precursor cell leukemia (CD56+, CD4-, CD7+, CD33+)
    • (d) Blastic plasmacytoid dendritic cell neoplasm (CD4+, CD56+, CD123+, CD7 variable, CD33-); frequent skin lesions, aggressive, poor prognosis (Am J Surg Pathol 2003;27:1366)
  • Stem cell transplantation may improve survival
Case Reports
Clinical Images
Images hosted on other servers:

50 × 60 mm nontender,
nonitching, dark red
tumor with smooth
surface on abdomen
Micro Images
Images hosted on other servers:

Various images