Skin nonmelanocytic tumor
Lymphoma and related disorders
Acute lymphoblastic lymphoma

Topic Completed: 1 June 2012

Revised: 4 April 2019

Copyright: 2001-2018,, Inc.

PubMed search: acute lymphoblastic lymphoma [title]

Christopher S. Hale, M.D.
Page views in 2018: 197
Page views in 2019 to date: 269
Cite this page: Hale C. Acute lymphoblastic lymphoma. website. Accessed December 6th, 2019.
Definition / general
  • Most common cutaneous lymphoma in children; rare in adults
  • Aggressive behavior
  • Either B cell (CD19+, CD20+, CD79a+), T cell (surface CD3+) or non B, non T (negative for B cell markers and CD3)
  • T cell subtypes have best prognosis
  • Non B, non T include:
    • (a) CD7+ stem cell lymphoma (CD7+, CD4-, CD56-, CD33 variable)
    • (b) blastic NK lymphoma (CD56+, CD4-, CD33-, CD123-, CD7 variable)
    • (c) myeloid / NK precursor cell leukemia (CD56+, CD4-, CD7+, CD33+)
    • (d) Blastic plasmacytoid dendritic cell neoplasm (CD4+, CD56+, CD123+, CD7 variable, CD33-); frequent skin lesions, aggressive, poor prognosis (Am J Surg Pathol 2003;27:1366)
  • Stem cell transplantation may improve survival
Case reports
Clinical images

Images hosted on other servers:

50 × 60 mm nontender,
nonitching, dark red
tumor with smooth
surface on abdomen

Microscopic (histologic) images

Images hosted on other servers:

Various images

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