Skin nonmelanocytic tumors
Other tumors of skin

Topic Completed: 1 September 2012

Revised: 4 April 2019

Copyright: 2001-2016,, Inc.

PubMed search: (cutaneous) leiomyosarcoma [title] skin

Christopher S. Hale, M.D.
Page views in 2018: 738
Page views in 2019 to date: 576
Cite this page: Hale C. Leiomyosarcoma. website. Accessed September 19th, 2019.
Definition / general
  • Malignant smooth muscle tumor similar to counterparts elsewhere
  • Typically larger than leiomyomas with vascular invasion
  • Recurs, but only rarely metastasizes
  • May be associated with HIV infection
Case reports
Microscopic (histologic) description
  • Cellular lesions of smooth muscle type cells with atypia, necrosis and mitotic activity
  • May have prominent vascular pattern, clear cell features, desmoplasia
Microscopic (histologic) images
Images hosted on other servers:

Various images

Positive stains
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