Skin - Nonmelanocytic tumors
Other tumors of skin

Author: Christopher Hale, M.D. (see Authors page)

Revised: 5 October 2016, last major update September 2012

Copyright: (c) 2001-2016,, Inc.

PubMed search: (cutaneous) leiomyosarcoma [title] skin

Cite this page: Leiomyosarcoma. website. Accessed December 12th, 2018.
Definition / general
  • Malignant smooth muscle tumor similar to counterparts elsewhere
  • Typically larger than leiomyomas with vascular invasion
  • Recurs, but only rarely metastasizes
  • May be associated with HIV infection
Case reports
Microscopic (histologic) description
  • Cellular lesions of smooth muscle type cells with atypia, necrosis and mitotic activity
  • May have prominent vascular pattern, clear cell features, desmoplasia
Microscopic (histologic) images
Images hosted on other servers:

Various images

Positive stains