Table of ContentsDefinition / General | Case Reports | Micro Description | Micro Images | Positive Stains | Molecular / Cytogenetics Description
Cite this page: Malignant peripheral nerve sheath tumor (MPNST). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticMPNST.html. Accessed December 8th, 2016.
Definition / General
- Hypercellular, plexiform fascicles of neural cells, high mitotic activity, significant pleomorphism
Molecular / Cytogenetics Description
- Numerous cytogenetic abnormalities
- Triploidy common
- Most frequent translocations are 7p22 and 1p21, 7p11 and 14q11 (not necessarily cutaneous tumors, Int J Cancer 1995;61:793)