Skin nonmelanocytic tumor
Lymphoma and related disorders - T cell / NK cell neoplasms
NK / T cell lymphoma, extranodal, nasal type


Topic Completed: 1 July 2012

Revised: 12 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: NK/T cell lymphoma [title] nasal

Christopher S. Hale, M.D.
Page views in 2018: 535
Page views in 2019 to date: 295
Cite this page: Hale CS. NK / T cell lymphoma, extranodal, nasal type. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticNKTcell.html. Accessed July 22nd, 2019.
Definition / general
  • Aggressive tumors, usually in GI tract, less commonly in skin
  • More common in Asia and South American than Western countries
  • Estimated 5 year survival: 0%
Case reports
Clinical images

Contributed by Dr. Mark R. Wick
Microscopic (histologic) description
  • May involve epidermis, dermis or subcutis
  • Polymorphous lymphoid infiltrate with eosinophils, plasma cells, histiocytes
  • Lymphocytes are usually large pleomorphic cells with vesicular nuclei and prominent nucleoli
  • Also medium or small with irregular nuclei
  • Usually angiocentric (52%) with necrosis (62%)
  • Apoptosis common
  • Occasionally clear cytoplasm
Microscopic (histologic) images

Contributed by Dr. Mark R. Wick

CD56

CD57

EBV in situ hybridization



Images hosted on other servers:

Tumor from various sites, including skin

Positive stains
Negative stains
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