Skin tumor - Nonmelanocytic - Acquired (tufted) angioma

Home Chapter Home Jobs Conferences Fellowships Books

Skin - Nonmelanocytic tumors

Vascular tumors

Acquired (tufted) angioma

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 16 July 2012, last major update July 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Also called Nakagawa’s angioblastoma
● Benign, juvenile or infantile hemangioendothelioma
● May be the same entity as kaposiform hemangioendothelioma
● Slowly enlarging multiple red plaques on shoulders and upper back of children or teenagers

Case reports
=========================================================================

● Congenital tumor (Dermatology Online Journal 16;5:2)
● 2 month old boy with erythematous induration (Ann Dermatol 2010;22:426)

Clinical images
=========================================================================

Various images

Gross description
=========================================================================

● Subcutaneous dusky red nodule

Micro description
=========================================================================

● Multiple vascular lobules similar to pyogenic granuloma but more cellular, resembling cannonballs, and with semilunar vessel at periphery of lobule (versus central and open vessel in pyogenic granuloma)
● Variable mitotic figures, no atypia

Micro images
=========================================================================

(A) Cannon ball distribution of small discrete vascular tufts are found throughout the dermis
(B) A lobule composed of bloodless aggregates of round dilated capillaries surrounded by crescent-shaped vascular structures

Positive stains
=========================================================================

● Ulex europaeus and factor VIII related antigen only in endothelium of larger vascular channels

Differential diagnosis
=========================================================================

● Hemangioma, pyogenic granuloma, sarcoma

End of Skin - Nonmelanocytic tumors > Vascular tumors > Acquired (tufted) angioma

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).