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Skin - Nonmelanocytic tumors

Vascular tumors

Angiokeratoma


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 16 July 2012, last major update July 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Vascular lesion characterized by superficial vascular ectasia and overlying acanthosis or hyperkeratosis
● Solitary or diffuse

Five types with similar histology:
(a) angiokeratoma of Mibelli acral skin
(b) angiokeratoma of Fordyce scrotal skin
(c) angiokeratoma corporis diffusum seen in Fabry disease
(d) angiokeratoma circumscriptum usually congenital, associated with nevus flammeus, cavernous hemangioma
(e) solitary or multiple angiokeratomas

Case reports
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● 26 year old man with bleed from scrotal skin (Emerg Med J 2006 23;10:e57)
● 31 year old man with papules on chest (Ann Dermatol 2010;22:66)

Gross description
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● Small red papule or nodule with verrucous surface

Gross images
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Various images

Micro description
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● Superficial vascular ectasia, acanthosis, hyperkeratosis

Micro images
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Contributed by Angel Fernandez-Flores, M.D., PhD, Hospital El Bierzo and Clinica Ponferrada, Spain


Various images

Differential diagnosis
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● Hemangiomas and other vascular malformations
● Lymphangioma

End of Skin - Nonmelanocytic tumors > Vascular tumors > Angiokeratoma


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