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Skin - Nonmelanocytic tumors

Vascular tumors

Angiokeratoma

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 16 July 2012, last major update July 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Vascular lesion characterized by superficial vascular ectasia and overlying acanthosis or hyperkeratosis
● Solitary or diffuse

Five types with similar histology:
(a) angiokeratoma of Mibelli – acral skin
(b) angiokeratoma of Fordyce – scrotal skin
(c) angiokeratoma corporis diffusum – seen in Fabry disease
(d) angiokeratoma circumscriptum – usually congenital, associated with nevus flammeus, cavernous hemangioma
(e) solitary or multiple angiokeratomas

Case reports
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● 26 year old man with bleed from scrotal skin (Emerg Med J 2006 23;10:e57)
● 31 year old man with papules on chest (Ann Dermatol 2010;22:66)

Gross description
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● Small red papule or nodule with verrucous surface

Gross images
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Various images

Micro description
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● Superficial vascular ectasia, acanthosis, hyperkeratosis

Micro images
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Contributed by Angel Fernandez-Flores, M.D., PhD, Hospital El Bierzo and Clinica Ponferrada, Spain


Various images

Differential diagnosis
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● Hemangiomas and other vascular malformations
● Lymphangioma

End of Skin - Nonmelanocytic tumors > Vascular tumors > Angiokeratoma

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