Skin nonmelanocytic tumor
Premalignant or noninvasive
Bowenoid papulosis


Topic Completed: 1 June 2012

Revised: 4 April 2019

Copyright: 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Bowenoid papulosis

Christopher S. Hale, M.D.
Page views in 2018: 2,464
Page views in 2019 to date: 1,301
Cite this page: Hale C. Bowenoid papulosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticbowenoidpapulosis.html. Accessed June 19th, 2019.
Definition / general
  • Multiple pigmented papular lesions of anogenital area, usually in young adults, resembling condyloma acuminatum
  • May regress spontaneously
  • Almost never invasive
Case reports
Clinical images

Images hosted on other servers:

Penile shaft

Gross description
  • Flat papules on anogenital skin
Microscopic (histologic) description
  • Resembles carcinoma in situ, but with localized acanthosis similar to condylomas
  • Low power view is “salt and pepper” due to dark nuclei and clear vacuolar cytoplasm
  • Usually no adnexal involvement
Microscopic (histologic) images

Images hosted on other servers:

Acanthosis and dyskeratosis

Positive stains
Molecular / cytogenetics description
  • HPV type 16 is most common
Differential diagnosis
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