Skin - Nonmelanocytic tumors
Premalignant or noninvasive
Bowenoid papulosis

Author: Christopher Hale, M.D. (see Authors page)

Revised: 13 October 2016, last major update June 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Bowenoid papulosis

Cite this page: Bowenoid papulosis. website. Accessed October 23rd, 2016.
Definition / General
  • Multiple pigmented papular lesions of anogenital area, usually in young adults, resembling condyloma acuminatum
  • May regress spontaneously
  • Almost never invasive
Case Reports
Clinical Images

Images hosted on other servers:

Penile shaft

Gross Description
  • Flat papules on anogenital skin
Micro Description
  • Resembles carcinoma in situ, but with localized acanthosis similar to condylomas
  • Low power view is “salt and pepper” due to dark nuclei and clear vacuolar cytoplasm
  • Usually no adnexal involvement
Micro Images

Images hosted on other servers:

Acanthosis and dyskeratosis

Positive Stains
Molecular / Cytogenetics Description
  • HPV type 16 is most common
Differential Diagnosis