Skin nonmelanocytic tumor
Cysts
Bronchogenic cyst


Topic Completed: 1 January 2015

Minor changes: 5 October 2020

Copyright: 2002-2020, PathologyOutlines.com, Inc.

PubMed Search: Bronchogenic cyst [title] skin

Ghassan A. Tranesh, M.D.
Hong Qu, M.D.
Page views in 2019: 2,074
Page views in 2020 to date: 1,255
Cite this page: Tranesh G. Bronchogenic cyst. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticbronchogeniccyst.html. Accessed October 24th, 2020.
Definition / general
  • Bronchogenic cysts presenting in the skin are very rare, with fewer than 70 cases reported
Sites
  • Most are present at birth on the precordium or overlying the suprasternal notch
  • Occasionally occur near shoulder, back, scapula, neck, abdomen or chin or present at a later age
Pathophysiology
  • Believed to form from buds or diverticula that separate from foregut during development of the tracheobronchial tree
  • May be intrapulmonary or peripheral
  • Cutaneous bronchogenic cysts may result from subsequent sequestration outside the chest cavity following fusion of the mesenchymal bars of the sternum, or from active migration prior to fusion
Clinical features
  • 80% males
  • Variable presentation as cutaneous cystic nodule, sinus or papillomatous growth
  • Usually asymptomatic but may be tender or painful
  • Rarely are multiple
  • Treatment is surgical resection, if clinically indicated
Case reports
Clinical images

Images hosted on other servers:
Sinus in suprasternal notch

Sinus in suprasternal notch

Sinus opening

Sinus opening

Gross description
  • Skin nodule
Gross images

Images hosted on other servers:
Scapular bronchogenic cyst

Scapular bronchogenic cyst

Microscopic (histologic) description
  • Cutaneous bronchogenic cyst occurs within dermis or subcutaneous tissue
  • Lining is usually thrown into small folds
  • Epithelium is invariably ciliated, pseudostratified cuboidal or columnar, with mucus secreting goblet cells in 50% of cases
  • May have nonciliated cuboidal, columnar and stratified squamous epithelium
  • Smooth muscle supports the mucosa in 8% of cases
  • Lymphoid follicles are found in 25% of cases, and appear to be part of a secondary inflammatory response
  • Occasionally seromucinous glands or cartilage are present
  • Cutaneous lung tissue heterotopia, in which fully developed bronchioles and alveoli are present, is considered a variant
Microscopic (histologic) images

Images hosted on other servers:
Pseudostratified ciliated columnar epithelium

Pseudostratified ciliated columnar epithelium

Ciliated respiratory epithelium

Ciliated respiratory epithelium

Respiratory and squamous epithelium

Respiratory and squamous epithelium

Cytology description
Positive stains
Differential diagnosis
Back to top
Image 01 Image 02