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Skin - Nonmelanocytic tumors

Benign nonmelanotic epidermal tumors / tumor-like lesions

Cutaneous horn


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 25 June 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Also called cornu cutaneum
● Descriptive term for horn-like hyperkeratotic lesion
● Usually caused by actinic keratosis, squamous cell carcinoma, keratoacanthoma, verruca, seborrheic keratosis, inverted follicular keratosis

Case reports
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● 84 year old woman with cutaneous horn of dorsal hand (N Engl J Med 2008;359:10)

Clinical images
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Large cutaneous horn associated with squamous cell carcinoma

Gross description
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● Protruding skin lesion composed of compact keratin resembling a horn

Micro description
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● Usually epidermal type keratin (with granular layer)
● Occasionally has trichilemmoma-like features (no granular layer but deep red granules)

End of Skin - Nonmelanocytic tumors > Benign nonmelanotic epidermal tumors / tumor-like lesions > Cutaneous horn


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