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Skin - Nonmelanocytic tumors

Cysts

Cystadenoma

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 29 June 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Also called cutaneous ciliated cyst
● Usually extremities of teenage girls
● May have Mullerian derivation
● Rarely described in males (in males, may have distinct fetal eccrine duct origin)

Case reports
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● 16 year old girl with lesion on thumb (Am J Dermatopathol 2012;34:335)

Gross description
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● Usually solitary, cystic, subcutaneous nodule

Micro description
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● Fallopian tube-like epithelium with cylindrical ciliated cells, nonciliated columnar cells, cuboidal cells, intercalated round cells

Micro images
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Cystadenoma

Positive stains
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● ER/PR, EMA

Negative stains
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● Smooth muscle actin (SMA), S100, p63, gross cystic disease protein fluid (GCDPF-15), CEA

Differential diagnosis
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● Cutaneous endosalpingiosis

End of Skin - Nonmelanocytic tumors > Cysts > Cystadenoma

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