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Skin - Nonmelanocytic tumors

Cysts

Dermoid cyst (cutaneous)


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 29 June 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Resembles keratinous cysts of epidermal type, but also have hair adnexae
● Usually face of children along embryonic closure lines, diagnosis sometimes later

Case reports
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● 48 year old man with left postauriclar cyst, 31 year old woman with right postauricular cyst (Oncol Rep 2006;16:295)

Gross description
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● Cystic lesion of head and neck

Clinical images
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5 mm midline cyst with overlying scar


Excision of cyst

Micro description
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● Lined by stratified squamous epithelium, adnexal structures, keratin in lumen

Micro images
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Unilocular cyst within the dermis connects with multiple pilosebaceous units; surrounding dermis is mildly fibrotic, cyst lining is stratified and squamous

Positive stains
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● Suprabasal layer: CK1 and CK10
● Basal layer: CK14
● Sebaceous gland-like areas: CK14+ in sebaceous acinus
● Sebaceous duct: CK17

Differential diagnosis
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● Follicular cyst (infundibular type)
Vellus hair cyst
Steatocystoma

End of Skin - Nonmelanocytic tumors > Cysts > Dermoid cyst (cutaneous)


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