Skin nonmelanocytic tumor
Fibrous, fibrohistiocytic and myofibroblastic neoplasms
Sarcomas arising in DFSP

Topic Completed: 1 September 2012

Revised: 18 April 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Sarcomas arising in DFSP

See also: Dermatofibrosarcoma protuberans (DFSP), Myxoid variant of DFSP

Christopher S. Hale, M.D.
Page views in 2018: 1,137
Page views in 2019 to date: 1,228
Cite this page: Hale CS. Sarcomas arising in DFSP. website. Accessed September 22nd, 2019.
Definition / general
Case reports
  • Wide local excision
Microscopic (histologic) description
  • In fibrosarcomatous areas, spindle cells intersect at acute angles, chromatin is coarser than usual, increased mitotic activity
Microscopic (histologic) images

Images hosted on PathOut servers:

Fibrosarcoma arising in DFSP - DFSP cells trap fat cells, fibrosarcoma cells are more uniform

Fibrosarcoma cells are spindled, uniform and hyperchromatic and arranged in herringbone pattern

Pleomorphc, tumor cells are pleomorphic and have granular chromatin

Uncommon finding is hyoid nodules
containing cells with eosinophilic cytoplasm,
present in DFSP or fibrosarcomatous areas,
cells are actin+, CD34-, desmin-

Images hosted on other servers:

Mitotic activity

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