Skin nonmelanocytic tumors
Fibrous, fibrohistiocytic and myofibroblastic neoplasms
Fibroepithelial polyp


Topic Completed: 1 May 2015

Revised: 29 March 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Fibroepithelial polyp [title]
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Cite this page: Elwood H. Fibroepithelial polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticfibroepithelialpolyp.html. Accessed May 21st, 2019.
Definition / general
  • Also known as acrochordon, skin tag, soft fibroma, cutaneous papilloma, cutaneous tag, fibroma pendulum, fibroma molluscum
  • Common, benign skin lesion of adults
  • Usually occur on intertriginous areas (i.e. axilla, groin), face, neck, eyelids
  • Associated with diabetes, abnormal lipid profile, other components of metabolic syndrome (Eur J Dermatol 2012;22:106)
  • Multiple lesions can be seen in Birt-Hogg-Dube syndrome
  • May increase in number during pregnancy
Clinical features
  • Soft papilloma, flesh colored to dark brown, sessile to pedunculated
  • A few millimeters to multiple centimeters in size
  • Larger lesions often attach to skin by slender stalks
Prognosis and treatment
  • Benign lesions, excised for cosmetic reasons
Case reports
Clinical images

Images hosted on other servers:

Penile fibroepithelial polyp

Fibroepithelial polyp
at posterior wall of
external auditory canal

Microscopic (histologic) description
  • Fibrovascular cores covered by squamous epithelium
  • Larger lesions may have a flattened epidermis
  • Smaller lesions can have epidermal hyperplasia or seborrheic keratosis-like changes
  • Central core composed of loose collagen with increased blood vessels
  • In larger lesion, may have a central core of adipose tissue
  • Pagetoid dyskeratosis is sometimes present as an incidental finding
  • May have ischemic necrosis due to torsion
Microscopic (histologic) images

Images hosted on other servers:

Acrochordon

Edematous stroma

Stellate fibroblasts

Dermal edema

Keratinized squamous epithelium

Epidermis with hyperkeratosis

Differential diagnosis
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