Skin - Nonmelanocytic tumors
Benign (nonmelanotic) epidermal tumors or tumor-like lesions
Fibroepithelial polyp

Author: Hillary Elwood, M.D. (see Authors page)

Revised: 3 October 2016, last major update May 2015

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Fibroepithelial polyp [title]

Cite this page: Fibroepithelial polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticfibroepithelialpolyp.html. Accessed December 10th, 2016.
Definition / General
  • Also known as acrochordon, skin tag, soft fibroma, cutaneous papilloma, cutaneous tag, fibroma pendulum, fibroma molluscum
  • Common, benign skin lesion of adults
  • Usually occur on intertriginous areas (i.e. axilla, groin), face, neck, eyelids
  • Associated with diabetes, abnormal lipid profile, other components of metabolic syndrome (Eur J Dermatol 2012;22:106)
  • Multiple lesions can be seen in Birt-Hogg-Dube syndrome
  • May increase in number during pregnancy
Clinical Features
  • Soft papilloma, flesh colored to dark brown, sessile to pedunculated
  • A few millimeters to multiple centimeters in size
  • Larger lesions often attach to skin by slender stalks
Prognosis and Treatment
  • Benign lesions, excised for cosmetic reasons
Case Reports
Clinical Images

Images hosted on other servers:

Penile fibroepithelial polyp

Brown sessile pedunculated papillomas

Fibroepithelial polyp at
posterior wall of
external auditory canal

Micro Description
  • Fibrovascular cores covered by squamous epithelium
  • Larger lesions may have a flattened epidermis
  • Smaller lesions can have epidermal hyperplasia or seborrheic keratosis-like changes
  • Central core composed of loose collagen with increased blood vessels
  • In larger lesion, may have a central core of adipose tissue
  • Pagetoid dyskeratosis is sometimes present as an incidental finding
  • May have ischemic necrosis due to torsion
Micro Images

Images hosted on other servers:

Acrochordon

Seborrheic keratosis-like hyperplasia

Edematous stroma

Stellate fibroblasts



Dermal edema

Keratinized squamous epithelium

Epidermis with hyperkeratosis

Polypoid fragment

Differential Diagnosis