Skin nonmelanocytic tumor
Vascular tumors
Glomus tumor



Topic Completed: 1 July 2012

Revised: 4 April 2019

Copyright: 2001-2016, PathologyOutlines.com, Inc.

PubMed search: glomus [title] tumor skin

Christopher S. Hale, M.D.
Page views in 2018: 4,847
Page views in 2019 to date: 2,910
Cite this page: Hale C. Glomus tumor. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticglomustumor.html. Accessed July 16th, 2019.
Definition / general
  • Usually painful subungual tumors
Case reports
Gross description
  • Painful nodule, often acral
Gross images
Images hosted on other servers:

Glomus tumor during exploration

Preoperative and
intraoperative
photographs views
of the lesion
Microscopic (histologic) description
  • Dermal or subcutaneous tumors, either solid or vascular, composed of glomus cells, a modified smooth muscle cell with abundant cytoplasm and oval nucleus
  • Either (a) solid variant - proliferation of glomus cells with no/rare vascular lumina or (b) vascular variant - abundant vascular lumina that may resemble cavernous hemangioma
Microscopic (histologic) images
Images hosted on PathOut server:

Courtesy of Angel Fernandez-Flores, M.D., Ph.D., Hospital El Bierzo and Clinica Ponferrada, Spain



Images hosted on other servers:

Blood vessels surrounded by proliferation of round cells
in fibrous stroma; vascular channels are lined by endo-
thelial cells and aggregates of round cells with darkly
staining round - ovoid nuclei and eosinophilic cytoplasm

Positive stains
Differential diagnosis
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