Skin tumor - Nonmelanocytic

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Skin - Nonmelanocytic tumors

Vascular tumors

Glomus tumor

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 16 July 2012, last major update July 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Usually painful subungual tumors

Case reports
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● 52 year old woman with 8 year history of progressively intense pain on finger (J Korean Neurosurg Soc 2010;48:185)

Gross description
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● Painful nodule, often acral

Gross images
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Glomus tumor during exploration

Preoperative and intraoperative photographs views of the lesion

Micro description
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● Dermal or subcutaneous tumors, either solid or vascular, composed of glomus cells, a modified smooth muscle cell with abundant cytoplasm and oval nucleus
● Either (a) solid variant - proliferation of glomus cells with no/rare vascular lumina or (b) vascular variant - abundant vascular lumina that may resemble cavernous hemangioma

Micro images
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Contributed by Angel Fernandez-Flores, MD, PhD, Hospital El Bierzo and Clinica Ponferrada, Spain

Blood vessels surrounded by proliferation of round cells in fibrous stroma; vascular channels are lined by endothelial cells and aggregates of round cells with darkly staining round-ovoid nuclei and eosinophilic cytoplasm

Positive stains
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● CD34

Differential diagnosis
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● Cavernous hemangioma
● Blue rubber bleb nevus syndrome (multiple tumors)
● Acrospiroma

End of Skin - Nonmelanocytic tumors > Vascular tumors > Glomus tumor

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