Skin tumor - Nonmelanocytic - Hair follicle nevus

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Skin - Nonmelanocytic tumors

Benign nonmelanotic epidermal tumors / tumor-like lesions

Hair follicle nevus

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 20 June 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Rare, congenital, hamartomatous
● Usually on face

Case reports
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● 2 year old boy with nose nodule (Pediatr Dermatol 2008;25:60)
● 26 year old man with small soft nodules on his nose since childhood (Eur J Dermatol 2008;18:185)
● In a distribution following Blaskho's lines (J Am Acad Dermatol 2002;46:S125)

Dermoscopy
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● Many uniform hair follicles and an interfollicular pseudo-pigment network in the nodules

Gross description
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● Papule or plaque with vellus hairs

Micro description
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● Well-differentiated hair follicles and sebaceous glands
● No cartilage (seen in accessory tragus), central cysts or a central canal (seen in trichofolliculoma)

Electron macroscopy description
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● Follicular germ cells present
● Active fibroblasts around the follicles merge with colloid substance (J Dermatol 2001;28:324)

Differential diagnosis
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● Accessory tragus, trichofolliculoma

End of Skin - Nonmelanocytic tumors > Benign nonmelanotic epidermal tumors / tumor-like lesions > Hair follicle nevus

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