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Skin - Nonmelanocytic tumors

Other tumors of skin

Hamartoma of scalp with ectopic meningothelial elements


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 14 September 2012, last major update September 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Scalp nodule that often arises during infancy containing meningothelial cells; may be diagnosed later in life
● Also called rudimentary meningocele or meningothelial hamartoma of scalp
● Related to meningioma of skin

Case reports
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● 9 year old girl with scalp lesion (Pediatr Dermatol 2011;28:677)
● 78 year old man with scalp lesion (Eur J Dermatol 2011;21:255)

Micro description
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● Whorls or dissecting pattern of meningothelial cells in dermis and subcutis
● Often psammoma bodies and cartilage
● Center of lesion may have long cleft
● Adipose tissue, blood vessels, nerves admixed with lesion

Micro images
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H&E and immunostains

Positive stains
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● Vimentin, EMA

Negative stains
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● CD34, CD31, factor VIII related antigen, AE1/AE3, S100 and alpha-smooth muscle actin

Differential diagnosis
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● Metastatic carcinoma, spindle cell/pleomorphic lipoma

End of Skin - Nonmelanocytic tumors > Other tumors of skin > Hamartoma of scalp with ectopic meningothelial elements


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