Skin - Nonmelanocytic tumors
Adnexal tumors - apocrine sweat glands
Hidradenoma papilliferum

Author: Christopher Hale, M.D. (see Authors page)

Revised: 5 October 2016, last major update June 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Hidradenoma papilliferum [title]

Cite this page: Hidradenoma papilliferum. website. Accessed October 23rd, 2016.
Definition / General
  • Also called papillary hidradenoma
  • Most common neoplasm of anogenital mammary-like glands
  • Exclusively in women
  • Perianal or vulvar (similar frequency in labia majora and labia minora)
  • Rare ectopic├╣ cases from eyelid, nasal area, breast
Case Reports
  • Slow-growing, firm, reddish nodule, may ulcerate
Clinical Images

Images hosted on PathOut servers:

Vulva, courtesy of Mark R. Wick, M.D.

Images hosted on other servers:

Lesions on labia majora

Nose lesion

Micro Description
  • Papillary fronds, ducts lined by apocrine type cells that show decapitation secretion and fibrous stroma
Micro Images

Images hosted on PathOut servers:

Case of the Week #343

Courtesy of Dr. Mark R. Wick:

Images hosted on other servers:

Lesion on labia majora

Lesion on nose

Cytology Description
  • Monomorphic population of cohesive cells with uniform pale staining nuclear chromatin, orderly nuclear placement, and round globules of metachromatic staining hyalinized material (Diagn Cytopathol 1994;10:60)
Negative Stains