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Skin - Nonmelanocytic tumors

Lymphoma and related disorders

Hodgkin’s lymphoma of skin


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 15 July 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Usually indicates stage IV disease
● Rarely is primary in skin

Case reports
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● 54 year old man with solitary cutaneous ulcer (Dermatol Online J 15;5:5)

Clinical images
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Ulcerating skin lesion due to Hodgkin lymphoma

Gross description
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● Nodules or papules distal to involved lymph nodes

Micro images
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Reed-Sternberg cells and CD30

Positive stains
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● CD15/Leu15, CD30

Negative stains
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● EMA, CD3, CD20

Differential diagnosis
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● Mycosis fungoides
● Cutaneous T cell lymphoma / granulomatous slack skin disease
● Lymphomatoid papulosis
● Anaplastic large cell lymphoma

Additional references
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J Am Acad Dermatol 2008;58:295

End of Skin - Nonmelanocytic tumors > Lymphoma and related disorders > Hodgkin’s lymphoma of skin


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