Skin nonmelanocytic tumor
Fibrous, fibrohistiocytic and myofibroblastic neoplasms
Keloid


Topic Completed: 1 September 2012

Revised: 19 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: Keloid [title] skin

Christopher S. Hale, M.D.
Page views in 2018: 8,988
Page views in 2019 to date: 5,907
Cite this page: Hale CS. Keloid. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocytickeloid.html. Accessed July 22nd, 2019.
Definition / general
  • Abnormal fibroblast reaction to injury
  • Usually in people of African descent, often in earlobe
  • High rate of recurrence after excision
Treatment
  • Corticosteroid injection
Clinical images
Images hosted on PathOut server:

Breast skin, courtesy of Dr. Mark R. Wick

Microscopic (histologic) description
  • Wide bands of collagen with large, brightly eosinophilic, glassy fibers
  • Also parallel fibroblasts and myofibroblasts
  • Mucinous pools after steroid injection
Microscopic (histologic) images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick

Molecular / cytogenetics description
Differential diagnosis
  • Complication of acne
  • Hyperplastic scar
  • Keloidal dermatofibroma
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