Skin nonmelanocytic tumor
Fibrous, fibrohistiocytic and myofibroblastic neoplasms

Topic Completed: 1 September 2012

Minor changes: 19 April 2019

Copyright: 2003-2019,, Inc.

PubMed search: Keloid [title] skin

Christopher S. Hale, M.D.
Page views in 2019: 10,748
Page views in 2020 to date: 4,617
Cite this page: Hale CS. Keloid. website. Accessed August 7th, 2020.
Definition / general
  • Abnormal fibroblast reaction to injury
  • Usually in people of African descent, often in earlobe
  • High rate of recurrence after excision
  • Corticosteroid injection
Clinical images
Images hosted on PathOut server:

Breast skin, courtesy of Dr. Mark R. Wick

Microscopic (histologic) description
  • Wide bands of collagen with large, brightly eosinophilic, glassy fibers
  • Also parallel fibroblasts and myofibroblasts
  • Mucinous pools after steroid injection
Microscopic (histologic) images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick

Molecular / cytogenetics description
Differential diagnosis
  • Complication of acne
  • Hyperplastic scar
  • Keloidal dermatofibroma
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