Skin - Nonmelanocytic tumors
Other tumors of skin
Leiomyoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 5 October 2016, last major update September 2012

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PubMed search: leiomyoma [title] skin



Cite this page: Leiomyoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticleiomyoma.html. Accessed December 10th, 2016.
Definition / General
  • Divided into lesions of nipple or scrotum, pilar leiomyoma or solitary angioleiomyoma (vascular leiomyoma) usually in subcutis
  • May be very painful

Familial cutaneous leiomyomatosis (Reed syndrome):
Micro Description
  • Intersecting smooth muscle fascicles
  • May have scattered bizarre hyperchromatic nuclei (symplastic leiomyoma)
  • No atypia, no mitotic activity, no necrosis

Pilar leiomyoma:
  • Dermal intersecting fascicles of eosinophilic spindle cells with plump, cigar shaped nuclei with dermal collagen bundles
Micro Images
Images hosted on PathOut server:

Courtesy of Dr. Angel Fernandez-Flores, M.D., Ph.D, Hospital El Bierzo and Clinica Ponferrada, Spain:

Various images

Positive Stains
Negative Stains
Differential Diagnosis