Skin nonmelanocytic tumor
Vascular tumors
Lymphangioma / lymphatic malformation


Topic Completed: 1 August 2012

Revised: 16 April 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed search: lymphangioma [title] skin

Related topics: Soft tissue chapter

Christopher S. Hale, M.D.
Page views in 2018: 1,062
Page views in 2019 to date: 1,585
Cite this page: Hale CS. Lymphangioma / lymphatic malformation. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticlymphangioma.html. Accessed October 22nd, 2019.
Definition / general
  • Usually infants or children age 5 years or less
  • Neck, axilla, breast, chest, buttock, thigh
  • Either superficial (lymphangioma circumscriptum, associated with surgery or radiotherapy for breast carcinoma), cystic (cystic hygroma) or deep (lymphangioma cavernosum)
Case reports
Treatment
  • Excision, but 25% recur
Microscopic (histologic) description
  • Grouped translucent papules with thin vascular lumina that impinge on epidermis
  • Often deep remnants in subcutaneous tissue
Microscopic (histologic) images

Contributed by V. Pavithra, M.D.

Board review question #1
Which of the following statements is true regarding lymphatic malformations?

A. They typically arise in senior adults.
B. They are unaffected by hormonal changes.
C. They may recur after excision.
D. They are distinctive and unlikely to be confused with other entities.
Board review answer #1
C. They may recur after excision. Lymphatic malformations are congenital and usually detected at birth or in the first few years of life. They may be affected by pubertal or pregnancy related hormones. There is a broad differential diagnosis including (acquired) lymphangiectasia, metastatic carcinoma, verrucae, molluscum, hemangioma, angiokeratoma and lymphangioendothelioma.
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