Skin - Nonmelanocytic tumors
Lymphoma and related disorders
Lymphoid hyperplasia

Author: Christopher Hale, M.D. (see Authors page)

Revised: 11 October 2016, last major update June 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: Lymphoid hyperplasia [title]

Cite this page: Lymphoid hyperplasia. website. Accessed October 16th, 2018.
Definition / general
  • Nonspecific finding
  • May be due to trauma, infection, arthropods
Clinical images
Images hosted on PathOut server:

Breast skin, courtesy of Dr. Mark R. Wick

Gross description
  • Solitary nodules or plaques
Microscopic (histologic) description
  • Lymphocytic and histiocytic infiltrate with tingible body macrophages, plasma cells, eosinophils
  • Often germinal cells or lymphoid follicles, hyperplastic vessels or epidermal hyperplasia
  • Usually spares epidermis
Microscopic (histologic) images
Images hosted on PathOut server:

Breast skin

Various images

Florid idiopathic


Images hosted on other servers:

Various images

Positive stains
  • Both kappa and lambda light chain expression, both B and T cells
Differential diagnosis
  • MALT lymphoma: marginal zone cells, Dutcher bodies, sheets of plasma cells