Skin - Nonmelanocytic tumors
Lymphoma and related disorders
Lymphoid hyperplasia

Author: Christopher Hale, M.D. (see Authors page)

Revised: 11 October 2016, last major update June 2012

Copyright: (c) 2003-2016,, Inc.

PubMed search: Lymphoid hyperplasia [title]

Cite this page: Lymphoid hyperplasia. website. Accessed April 27th, 2017.
Definition / General
  • Nonspecific finding
  • May be due to trauma, infection, arthropods
Clinical Images
Images hosted on PathOut server:

Breast skin, courtesy of Dr. Mark R. Wick

Gross Description
  • Solitary nodules or plaques
Micro Description
  • Lymphocytic and histiocytic infiltrate with tingible body macrophages, plasma cells, eosinophils
  • Often germinal cells or lymphoid follicles, hyperplastic vessels or epidermal hyperplasia
  • Usually spares epidermis
Micro Images
Images hosted on PathOut server:

Breast skin

Various images

Florid idiopathic


Images hosted on other servers:

Various images

Positive Stains
  • Both kappa and lambda light chain expression, both B and T cells
Differential Diagnosis
  • MALT lymphoma: marginal zone cells, Dutcher bodies, sheets of plasma cells