Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Skin - Nonmelanocytic tumors

Carcinoma (non-adnexal)

Mucoepidermoid carcinoma


Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 15 July 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Very rare in skin (~30 cases reported)
● Probable sweat gland origin
● Resembles similar tumor of salivary gland
● Usually low to intermediate grade

Case reports
=========================================================================

● 66 year old man with lesion on pinna (J Cutan Pathol 1991;18:56)
● 72 year old man with plaque on scalp (J Cutan Pathol 2003;30:652)
● 79 year old white woman with axillary mass (Am J Surg Pathol 2005;29:131)

Gross description
=========================================================================

● Flesh-colored nodules, painless

Micro description
=========================================================================

● Circumscribed, not attached to surface
● Dermal lobules or cystic growth of low grade epidermoid, intermediate, mucinous cells and clear cells
● Peritumoral fibrosis is common

Positive stains
=========================================================================

● Mucin, keratin, CK7, pCEA, EMA

Negative stains
=========================================================================

● CK20, GCDFP-15

Differential diagnosis
=========================================================================

● Adenosquamous carcinoma: high grade tumor, often involves epidermis, adenocarcinoma component is well-differentiated
● Metastatic salivary gland tumor: usually high grade
● Mucinous metaplasia

End of Skin - Nonmelanocytic tumors > Carcinoma (non-adnexal) > Mucoepidermoid carcinoma


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).