Skin nonmelanocytic tumor
Adnexal tumors
Sweat gland derived (apocrine & eccrine glands)
Syringocystadenoma papilliferum

Topic Completed: 1 June 2012

Minor changes: 4 April 2019

Copyright: 2002-2017,, Inc.

PubMed Search: Syringocystadenoma papilliferum [title]

Christopher S. Hale, M.D.
Page views in 2019: 12,655
Page views in 2020 to date: 6,527
Cite this page: Hale C. Syringocystadenoma papilliferum. website. Accessed August 6th, 2020.
Definition / general
  • Also known as papillary syringadenoma
  • Warty tumor of scalp, neck and face that occurs at any age
  • Slow growing or a recent change in an apparent birthmark
  • 1/3 have adjacent nevus sebaceus, 10% have adjacent basal cell carcinoma
  • Eccrine syringofibroadenoma: with prominent fibrous stroma
  • Syringocystadenocarcinoma papilliferum: malignant counterpart
Clinical images

Images hosted on other servers:

Syringocystadenoma papilliferum

Microscopic (histologic) description
  • Glandular papillary proliferation connected to skin surface, dense plasma cell infiltrate
Microscopic (histologic) images

Images hosted on PathOut server:

Images contributed by Joel Pinczewski MD PhD, Australia


Syringocystadenoma Papilliferum: right - increased magnification

Images hosted on other servers:


Images hosted on Flickr:

Ulcerated scalp mass of 20 years duration, images courtesy of Dr. Okechukwu Okafor

Positive stains
  • Plasma cells are IgA+, IgG+
Back to top