Skin nonmelanocytic tumor
Adnexal tumors - eccrine sweat glands
Syringocystadenoma papilliferum




Topic Completed: 1 June 2012

Revised: 4 April 2019

Copyright: 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Syringocystadenoma papilliferum [title]
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Cite this page: Hale C. Syringocystadenoma papilliferum. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticpapillarysyringadenoma.html. Accessed April 25th, 2019.
Definition / general
  • Also known as papillary syringadenoma
  • Warty tumor of scalp, neck and face that occurs at any age
  • Slow growing or a recent change in an apparent birthmark
  • 1/3 have adjacent nevus sebaceus, 10% have adjacent basal cell carcinoma
  • Eccrine syringofibroadenoma: with prominent fibrous stroma
  • Syringocystadenocarcinoma papilliferum: malignant counterpart
Clinical images

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Syringocystadenoma papilliferum

Microscopic (histologic) description
  • Glandular papillary proliferation connected to skin surface, dense plasma cell infiltrate
Microscopic (histologic) images

Images hosted on PathOut server:

Images contributed by Joel Pinczewski MD PhD, Australia

 

Syringocystadenoma Papilliferum: right - increased magnification



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Apocrine



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Ulcerated scalp mass of 20 years duration, images courtesy of Dr. Okechukwu Okafor

Positive stains
  • Plasma cells are IgA+, IgG+
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