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Skin - Nonmelanocytic tumors

Benign nonmelanotic epidermal tumors / tumor-like lesions

Pseudoepitheliomatous hyperplasia

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 25 June 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Due to reparative changes associated with chronic irritation, granular cell tumor, melanoma, North American blastomycosis, Spitz nevi, syphilis, trauma, tuberculosis, ulcer

Micro description
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● Deep tongues of epithelial cells that may appear invasive but are thin, elongated, anastomosing and surrounded by inflammatory cells (acute/subacute)
● Also dermal fibrosis and vascular proliferation
● No/rare atypia

Micro images
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Pseudoepitheliomatous hyperplasia

Differential diagnosis
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● Squamous cell carcinoma: thicker strands, atypia, usually no prominent inflammatory infiltrate

End of Skin - Nonmelanocytic tumors > Benign nonmelanotic epidermal tumors / tumor-like lesions > Pseudoepitheliomatous hyperplasia

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