Skin nonmelanocytic tumor
Vascular tumors
Capillary / pyogenic granuloma

Topic Completed: 1 August 2012

Revised: 9 September 2019

Copyright: 2003-2019,, Inc.

PubMed search: pyogenic [title] granuloma skin

Christopher S. Hale, M.D.
Page views in 2018: 26,005
Page views in 2019 to date: 23,311
Cite this page: Hale CS. Capillary / pyogenic granuloma. website. Accessed September 22nd, 2019.
Definition / general
  • Very common; rapidly growing polypoid red mass surrounded by thickened epidermis, often in finger or lips
  • Also called granuloma pyogenicum, lobular capillary hemangioma
  • May be associated with keratinous cyst
  • Benign, often regresses spontaneously
  • May be disseminated, occur within port wine stains, be in deep dermis / subcutis or be intravenous

  • Classic polypoid, dermal, subcutaneous, intravenous, eruptive, with multiple satellites
  • None or excision (may recur as multiple satellites)
Clinical images
Images hosted on PathOut server:

Pyogenic granuloma, c/o Dr. Mark R. Wick

Gross description
  • Fleshy cutaneous tumor
Microscopic (histologic) description
  • Lobular pattern of vascular proliferation with inflammation and edema resembling granulation tissue
  • Thin epidermis at top with variable ulceration
  • Acanthosis and hyperkeratosis at sides
  • Central branching vessel is called capillary or vascular lobule, with no / rare red blood cells, surrounded by endothelial cells
  • Variable mitotic activity
  • Deep lesions often lack edema and inflammation
Microscopic (histologic) images
Images hosted on PathOut server:

Pyogenic granuloma, courtesy of Dr. Mark R. Wick

Images hosted on other servers:

Low magnification

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