Skin - Nonmelanocytic tumors
Vascular tumors
Pyogenic granuloma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 7 October 2016, last major update August 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: pyogenic [title] granuloma skin

Cite this page: Pyogenic granuloma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticpyogenicgranuloma.html. Accessed December 3rd, 2016.
Definition / General
  • Very common; rapidly growing polypoid red mass surrounded by thickened epidermis, often in finger or lips
  • Also called granuloma pyogenicum, lobular capillary hemangioma
  • May be associated with keratinous cyst
  • Benign, often regresses spontaneously
  • May be disseminated, occur within port wine stains, be in deep dermis / subcutis or be intravenous

Variants:
  • Classic polypoid, dermal, subcutaneous, intravenous, eruptive, with multiple satellites
Treatment
  • None or excision (may recur as multiple satellites)
Clinical Images
Images hosted on PathOut server:

Pyogenic granuloma, c/o Dr. Mark R. Wick

Gross Description
  • Fleshy cutaneous tumor
Micro Description
  • Lobular pattern of vascular proliferation with inflammation and edema resembling granulation tissue
  • Thin epidermis at top with variable ulceration
  • Acanthosis and hyperkeratosis at sides
  • Central branching vessel is called capillary or vascular lobule, with no / rare red blood cells, surrounded by endothelial cells
  • Variable mitotic activity
  • Deep lesions often lack edema and inflammation
Micro Images
Images hosted on PathOut server:

Pyogenic granuloma, courtesy of Dr. Mark R. Wick



Images hosted on other servers:

Low magnification