Skin - Nonmelanocytic tumors
Adnexal tumors - eccrine sweat glands
Microcystic adnexal carcinoma

Author: Christopher Hale, M.D. (see Authors page)

Revised: 5 October 2016, last major update June 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Microcystic adnexal carcinoma [title]

Cite this page: Microcystic adnexal carcinoma. website. Accessed October 27th, 2016.
Definition / General
  • Also called sclerosing sweat gland carcinoma
  • Slow growing nodule or plaque, usually on upper lip or face
  • Difficult to achieve negative surgical margins, commonly recurs, metastases very rare
  • Perineural invasion common
Case Reports
Gross Description
  • Slow-growing facial plaque
Gross Images

Images hosted on other servers:

Large, hard-rubbery neoplasm

Micro Description
  • Cords and nests of bland keratinocytes, keratin cysts and ductal differentiation
  • Dense collagenous stroma
  • Is invasive, may extend into subcutis or perineural spaces
  • Resembles syringoma
  • Rarely is sebaceous differentiation
Micro Images

Images hosted on PathOut servers:

Courtesy of Mark R. Wick, M.D.

Differential Diagnosis