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Skin - Nonmelanocytic tumors

Adnexal tumors-sebaceous glands

Sebaceous adenoma

Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 14 July 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Hyperplasia of sebaceous lobules with expasion of germinative basaloid cell layers at periphery
● Unrelated to adenoma sebaceum (facial angiofibromas of tuberous sclerosis)
● Associated with Muir-Torré Syndrome (Histopathology 2010;56:133)

Clinical images
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In patient with Muir-Torre Syndrome

Gross description
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● Papule/nodule on face/scalp

Micro description
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● Nodular lobulated growth with dark and light areas corresponding to generative cells (dark) and sebaceous cells (light) with cytoplasmic lipid vacuoles
● Not as organoid as sebaceous hyperplasia

Micro images
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Various images

Differential diagnosis
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● Sebaceous hyperplasia
● Sebaceous carcinoma
● Other lesions with sebaceous differentiation

End of Skin - Nonmelanocytic tumors > Adnexal tumors-sebaceous glands > Sebaceous adenoma

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