Table of ContentsDefinition / General | Case Reports | Micro Description | Micro Images | Positive Stains | Negative Stains
Cite this page: Sinus histiocytosis with massive lymphadenopathy. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticsinushistiocytosis.html. Accessed December 10th, 2016.
Definition / General
- Very rare disorder, usually prominent cervical lymphadenopathy, but may involve skin
- Also called Rosai-Dorfman disease
- Infiltration by sheets of large histiocytes with granular eosinophilic cytoplasm, large, round and vesicular nuclei, prominent nucleoli, and accompanied by plasma cells and lymphocytes, emperipolesis (histiocytes with intracytoplasmic lymphocytes)