Skin - Nonmelanocytic tumors
Adnexal tumors - eccrine sweat glands
Sweat gland carcinoma
Reviewer: Christopher Hale, M.D. (see Reviewers page)
Revised: 4 July 2012, last major update June 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.
● Usually adults
● Difficult to diagnose
● May be life threatening
● Microcystic carcinoma, adenoid cystic carcinoma, mucinous carcinoma, extramammary Pagetís disease, mucoepidermoid carcinoma
● Ductal adenocarcinoma, aggressive digital papillary adenocarcinoma, acrospirocarcinoma
● Porocarcinoma, clear cell acrospirocarcinoma
● Signet ring cell carcinoma, papillary syringadenocarcinoma
● Also includes adenoid cystic carcinoma, apocrine carcinoma, malignant acrospiroma, malignant chondroid syringoma (malignant mixed tumor), malignant dermal cylindroma, malignant eccrine poroma (most common), malignant myoepithelioma, malignant syringoma (syringoid eccrine carcinoma), mucinous syringometaplasia
● Benign sweat gland tumors can also undergo malignant transformation to high grade carcinoma
● May resemble breast carcinoma, renal cell carcinoma, basal cell carcinoma
● GCDFP-15, estrogen receptor, keratin, EMA, CEA
● Metastatic breast carcinoma
● Renal cell carcinoma
End of Skin - Nonmelanocytic tumors > Adnexal tumors - eccrine sweat glands > Sweat gland carcinoma
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