Skin - Nonmelanocytic tumors
Lymphoma and related disorders
Woringer-Kolopp disease

Author: Christopher Hale, M.D. (see Authors page)

Revised: 10 October 2016, last major update July 2012

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: Woringer-Kolopp disease [title]

Cite this page: Woringer-Kolopp disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/skintumornonmelanocyticworingerkolopp.html. Accessed December 10th, 2016.
Definition / General
  • Also called pagetoid reticulosis
  • Indolent, T cell cutaneous proliferative disorder related to mycosis fungoides
  • 2:1 male to female incidence
  • Usually solitary lesion on distal extremities
  • Disseminated lesions called Ketron-Goodman disease
Case Reports
Treatment
  • May include electron beam, pharmacological intervention, psoralen plus ultraviolet A (PUVA) photochemotherapy, radiotherapy, or surgery (J Clin Aesthet Dermatol 2010;3:46)
Clinical Images
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10 × 10mm plaque

Gross Description
  • Solitary erythematosquamous patch
Micro Description
  • Monomorphic intraepidermal infiltrate of mycosis fungoides-like cells, in Paget's disease type pattern
Micro Images
Images hosted on PathOut server:

Courtesy of Dr. Mark R. Wick



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Psoriasiform hyperplasia

CD8, CD4

Positive Stains
  • Either CD4+ CD8+ or CD4- CD8-
Differential Diagnosis