Small bowel (small intestine)
Infectious disorders

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 14 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: CMV small bowel[TIAB]

Cite this page: Gulwani, H. CMV. website. Accessed October 15th, 2018.
Definition / general
  • CMV infections associated with immunosuppression, HIV; usually reflects disseminated infection if present in gut
  • May cause necrotizing injury and perforation
  • CMV duodenitis may present with bleeding or ulceration
Microscopic (histologic) description
  • Inclusions in endothelial cells, fibroblasts, smooth muscle cells
  • Necrosis and granulation tissue associated with moderate / marked lymphoplasmacytic infiltrate (Scand J Gastroenterol 2011;46:1228)
  • Small bowel allografts: circumscribed area of mucosal injury with few eosinophils (Transplant Proc 2010;42:2671)
Microscopic (histologic) images

Images hosted on other servers:

Various images

Images contributed by Dr. Hanni Gulwani:

38 year old man with CMV pouchitis, postsurgery for ulcerative colitis; note nucleomegaly with intranuclear inclusions