Small bowel (small intestine)
Hodgkin lymphoma

Topic Completed: 1 August 2012

Revised: 15 March 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Hodgkin lymphoma[TIAB] small bowel

Hanni Gulwani, M.B.B.S.
Page views in 2019: 133
Page views in 2020 to date: 23
Cite this page: Gulwani H. Hodgkin lymphoma. website. Accessed February 27th, 2020.
Definition / general
  • Stringent criteria suggested due to rarity of primary disease and possible confusion with secondary spread
  • Associated with inflammatory bowel disease or longstanding chronic inflammation, combined with chronic immunosuppression; in these cases, may be due to Epstein-Barr virus associated lymphoproliferation (Am J Surg Pathol 2000;24:66)
Case reports
  • Discontinuation of immunosuppressive therapy may be helpful
Gross description
  • Transmural involvement of bowel wall, often multifocal, associated with fissuring ulcers, diverticula with abscesses
Microscopic (histologic) description
  • Reed-Sternberg cells in background of lymphoid hyperplasia, occasional granulomas
Microscopic (histologic) images

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Various images

Positive stains
Negative stains
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