Small bowel (small intestine)
Benign tumors and tumor-like conditions
Idiopathic retroperitoneal fibrosis
Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 21 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.
● Fibrosis which develops in retroperitoneum, often at aortic bifurcation
● Associated with drug methylsergine, other fibrotic lesions (sclerosis of major bile ducts, Riedelís thyroiditis, inflammatory pseudotumor of orbit)
● IgG4 often involved in pathogenesis of idiopathic sclerosing lesion; associated with male gender
● Associated with lymphoma, which developed in 15% of patients
● 58 year old man with idiopathic sclerosing mesenteritis and retroperitoneal fibrosis (Korean J Gastroenterol 2011;58:221)
● With previous sclerosing mesenteritis and small bowel obstruction (Eur J Gastroenterol Hepatol 2006;18:1285)
● Not well circumscribed
● Widely scattered germinal centers and plasma cells in background of dense fibrosis
● Eosinophilic infiltration and oblitertaive phlebitis in IgG4 related cases (Am J Surg Pathol 2009;33:1833)
End of Small bowel (small intestine) > Benign tumors and tumor-like conditions > Idiopathic retroperitoneal fibrosis
This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.
All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at [email protected] with any questions (click here for other contact information).