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Small bowel (small intestine)

Other malignancies

Leiomyosarcoma


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Duodenal tumors - mean age 54 years (Am J Surg Pathol 2003;27:625)

Case reports
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● 43 year old woman with leiomyosarcoma of small intestine presenting as pelvic mass (Eur J Obstet Gynecol Reprod Biol 1996;66:187)
● 63 year old man with leiomyosarcoma of small intestine presenting as intussusception (Saudi J Gastroenterol 2005;11:170)

Gross description
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● Intraluminal, bulging, polypoid tumor (duodenal tumors - mean 14 cm)

Gross images
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Leiomyosarcoma of small bowel

Micro description
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● Resemble smooth muscle cells
● High grade features (pleomorphism, atypia, mitotic figures, necrosis)

Positive stains
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● Smooth muscle actin, desmin

Negative stains
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● CD34, CD117

End of Small bowel (small intestine) > Other malignancies > Leiomyosarcoma


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