Small bowel (small intestine)
Benign tumors and tumor-like conditions
Neurofibroma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 20 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Neurofibroma[TI] small bowel

Cite this page: Gulwani, H. Neurofibroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelNF.html. Accessed July 22nd, 2018.
Definition / general
  • Associated with multiple endocrine adenomatosis or von Recklinghausen disease (neurofibromatosis 1)
  • With NF1, also associated with hyperplasia of submucosal and myenteric nerve plexuses, mucosal ganglioneuromatosis, GI stromal tumors, gangliocytic paraganglioma
  • GISTs arising in NF1 do not express the typical sporadic GIST mutations of KIT exon 9, 11, 13 or 17 or PDGFRA exon 12 or 18; suggesting a different pathogenesis (Am J Surg Pathol 2006;30:90)
Case reports
Microscopic (histologic) images

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Colonic neurofibroma