Small bowel (small intestine)
Benign tumors and tumor-like conditions
Neurofibroma


Topic Completed: 1 August 2012

Revised: 13 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Neurofibroma[TI] small bowel
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Cite this page: Gulwani H. Neurofibroma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelNF.html. Accessed May 23rd, 2019.
Definition / general
  • Associated with multiple endocrine adenomatosis or von Recklinghausen disease (neurofibromatosis 1)
  • With NF1, also associated with hyperplasia of submucosal and myenteric nerve plexuses, mucosal ganglioneuromatosis, GI stromal tumors, gangliocytic paraganglioma
  • GISTs arising in NF1 do not express the typical sporadic GIST mutations of KIT exon 9, 11, 13 or 17 or PDGFRA exon 12 or 18; suggesting a different pathogenesis (Am J Surg Pathol 2006;30:90)
Case reports
Microscopic (histologic) images

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Colonic neurofibroma

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