Small bowel (small intestine)
Benign tumors and tumor-like conditions
Angiomyolipoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 16 February 2018, last major update May 2010

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Angiomyolipoma small bowel

See also: Kidney tumor chapter
Cite this page: Pernick, N. Angiomyolipoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelangiomyolipoma.html. Accessed April 21st, 2018.
Definition / general
  • Benign triphasic tumor composed of dysmorphic, thick walled blood vessels, smooth muscle that appears to spin off from vessel walls and mature lipid distended cells
Etiology
Clinical features
Case reports
Prognosis and treatment
Clinical images

Images hosted on PathOut server:

25 cm mass

Gross images

Images hosted on PathOut server:

25 cm mass



Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Benign triphasic tumor composed of dysmorphic, thick walled blood vessels, smooth muscle that appears to spin off from vessel walls and mature lipid distended cells
  • Tumors occasionally have bizarre epithelioid smooth muscle cells (Int J Surg Pathol 2000;8:67) and possible multinucleation
Microscopic (histologic) images

Images hosted on PathOut server:

Various images



Images hosted on other servers:

Various images

Negative stains
Differential diagnosis
  • Theoretically broad, encompassing smooth muscle and lipogenic tumors but narrowed when one carefully identifies the components of the tumor; few other tumors are immunoreactive for both smooth muscle and melanocytic markers
  • Leiomyomas and leiomyosarcomas have a prominent smooth muscle component but lack a prominent vascular or adipose component
  • Melanomas have prominent atypia, necrosis and infiltrative borders