Small bowel (small intestine) - Burkitt’s lymphoma

Home Chapter Home Jobs Conferences Fellowships Books

Small bowel (small intestine)

Lymphoma

Burkitt’s lymphoma

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● High grade lymphoma, usually in children
● Endemic cases in Africa usually do not present with GI involvement
● Sporadic cases in Western world and Middle East may present with ileocecal involvement, pain or obstruction

Case reports
=========================================================================

● 16 year old boy with acute abdomen (Cases J 2009;2:9322)
● 24 year old man with Burkitt's lymphoma of ileum and renal cell carcinoma.(Can J Surg 2008;51:E77)

Gross images
=========================================================================

Ileocecal valve tumor contributed by Dr. Kaveh Naemi, Irvine, California

Terminal ileum tumor

Micro description
=========================================================================

● Small, noncleaved, monomorphic cells with round nuclei, prominent multiple nucleoli, basophilic cytoplasm
● Vacuoles on touch prep
● Starry sky appearance on low power

Micro images
=========================================================================

Ileocecal valve tumor (courtesy of Dr. Kaveh Naemi, Irvine, California)

Above ileocecal valve tumor (left to right): CD20+, CD10+, Ki-67 strong, bcl2- (contributed by Dr. Kaveh Naemi, Irvine, California)

Terminal ileum tumor (left to right): H&E, CD10+, Ki-67 (strong)

Cytology images
=========================================================================

Touch prep

Positive stains
=========================================================================

● CD20, CD10

Negative stains
=========================================================================

● CD5, CD23

Molecular description
=========================================================================

● c-myc translocations of t(8;14) and others

Molecular images
=========================================================================

Terminal ileum tumor: c-myc by FISH

End of Small bowel (small intestine) > Lymphoma > Burkitt’s lymphoma

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).