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Small bowel (small intestine)

Infectious disorders

Cryptosporidium parvum


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 17 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Acid fast protozoa which causes self-limited disease in immunocompetent, but severe watery diarrhea resistant to most therapy in immunocompromised (J Biomed Res 2012;25:1)

Diagnosis
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● Acid-fast infective oocyst in stool

Micro description
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● 2-5 micron basophilic spherical structures attached to microvillus surface of epithelium
● Variable villus abnormality, may have eosinophils infiltrating mucosa

Micro images
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Various images

Positive stains
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● Giemsa, silver stains, PAS

Differential diagnosis
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● Mucin
● Cellular debris

End of Small bowel (small intestine) > Infectious disorders > Cryptosporidium parvum


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