Small bowel (small intestine)
Inflammatory disorders
Diaphragm disease


Topic Completed: 1 August 2012

Revised: 11 March 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Diaphragm disease[TIAB] small bowel
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Cite this page: Pernick N. Diaphragm disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallboweldiaphragmdisease.html. Accessed May 23rd, 2019.
Definition / general
Case reports
Treatment
Gross description
  • Segmentation of ileum by incomplete mucosal diaphragms, defined as thin circumferential membranes resembling the plica circularis, composed of mucosa and submucosa with accompanying fibrosis
  • Also ulceration, strictures, perforation
Gross images

Case of the Week #240

Various images



Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Thin circumferential membranes resembling plica circularis, composed of mucosa and submucosa with accompanying fibrosis
  • Neuromuscular and vascular hamartoma-like changes, eosinophilic enteritis and acute inflammation (Am J Clin Pathol 2008;130:518)
Microscopic (histologic) images

Case of the Week #240

H&E


Trichrome

Differential diagnosis
  • Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE): small intestinal strictures and ulcerations of unknown origin (World J Gastroenterol 2011;17:2873), characterized as atypical vasculitis presenting with unexplained stricture and ulceration of the small bowel in young and middle aged patients but without systemic inflammation; treated with steroids
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