Small bowel (small intestine)
Inflammatory disorders
Diaphragm disease

Author: Nat Pernick, M.D. (see Authors page)

Revised: 13 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Diaphragm disease[TIAB] small bowel

Cite this page: Pernick, N. Diaphragm disease. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallboweldiaphragmdisease.html. Accessed October 18th, 2018.
Definition / general
Case reports
Treatment
Gross description
  • Segmentation of ileum by incomplete mucosal diaphragms, defined as thin circumferential membranes resembling the plica circularis, composed of mucosa and submucosa with accompanying fibrosis
  • Also ulceration, strictures, perforation
Gross images

Images hosted on PathOut server:

Various images



Images hosted on other servers:

Various images

Microscopic (histologic) description
  • Thin circumferential membranes resembling plica circularis, composed of mucosa and submucosa with accompanying fibrosis
  • Neuromuscular and vascular hamartoma-like changes, eosinophilic enteritis and acute inflammation (Am J Clin Pathol 2008;130:518)
Microscopic (histologic) images

Images hosted on PathOut server:

H&E


Trichrome

Differential diagnosis
  • Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE): small intestinal strictures and ulcerations of unknown origin (World J Gastroenterol 2011;17:2873), characterized as atypical vasculitis presenting with unexplained stricture and ulceration of the small bowel in young and middle aged patients but without systemic inflammation; treated with steroids