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Small bowel (small intestine)

Other malignancies

Duodenal endocrine tumors


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 22 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Aggressive tumors - metastases common at diagnosis (21%)
● G cell (gastrin) tumors are associated with Zollinger-Ellison syndrome, MEN1 syndrome
● D cell (somatostatin) tumors are associated with neurofibromatosis 1 in blacks

Case reports
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● Duodenal gastrinoma with multiple gastric neuroendocrine tumors secondary to chronic Helicobacter pylori gastritis (Am J Surg Pathol 2012;36:935)

Gross description
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● 0.5 to 2 cm, smooth, round

Micro description
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● Features of carcinoid tumors
● Often G-cells or D-cells
● Usually glandular component present; psammoma bodies often present in D cell tumors

End of Small bowel (small intestine) > Other malignancies > Duodenal endocrine tumors


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