Small bowel (small intestine)
Other malignancies
Duodenal endocrine tumors

Topic Completed: 1 August 2012

Revised: 15 March 2019

Copyright: 2003-2019,, Inc.

PubMed Search: Duodenal endocrine tumors small bowel free full text[sb]
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Cite this page: Gulwani H. Duodenal endocrine tumors. website. Accessed May 24th, 2019.
Definition / general
  • Aggressive tumors - metastases common at diagnosis (21%)
  • G cell (gastrin) tumors are associated with Zollinger-Ellison syndrome, MEN1 syndrome
  • D cell (somatostatin) tumors are associated with neurofibromatosis 1 in blacks
Case reports
  • Duodenal gastrinoma with multiple gastric neuroendocrine tumors secondary to chronic Helicobacter pylori gastritis (Am J Surg Pathol 2012;36:935)
Gross description
  • 0.5 - 2 cm, smooth, round
Microscopic (histologic) description
  • Features of carcinoid tumors
  • Often G cells or D cells
  • Usually glandular component present; psammoma bodies often present in D cell tumors
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