Small bowel (small intestine)
Other malignancies
Duodenal endocrine tumors

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 23 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Duodenal endocrine tumors small bowel free full text[sb]

Cite this page: Gulwani, H. Duodenal endocrine tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelduodenalendocrine.html. Accessed October 16th, 2018.
Definition / general
  • Aggressive tumors - metastases common at diagnosis (21%)
  • G cell (gastrin) tumors are associated with Zollinger-Ellison syndrome, MEN1 syndrome
  • D cell (somatostatin) tumors are associated with neurofibromatosis 1 in blacks
Case reports
  • Duodenal gastrinoma with multiple gastric neuroendocrine tumors secondary to chronic Helicobacter pylori gastritis (Am J Surg Pathol 2012;36:935)
Gross description
  • 0.5 - 2 cm, smooth, round
Microscopic (histologic) description
  • Features of carcinoid tumors
  • Often G cells or D cells
  • Usually glandular component present; psammoma bodies often present in D cell tumors