Small bowel (small intestine)
Benign tumors and tumor-like conditions
Enteritis cystica profunda

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 16 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Enteritis cystica profunda small bowel

Cite this page: Gulwani, H. Enteritis cystica profunda. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelenteritiscystica.html. Accessed October 19th, 2018.
Definition / general
  • Mucosal glands and mucinous cysts in submucosa or deeper layer (J R Soc Med 2004;97:29, Arch Pathol Lab Med 2010;134:378)
  • Usually asymptomatic but may cause obstruction or intussuception
  • Pathogenesis: herniation, implantation after ulceration, mucosal microdiverticula and reepithelialization of fistulae (e.g. in Crohn's disease)
Microscopic (histologic) description
  • Mucosal glands and mucinous cysts in submucosa or deeper (subserosa) layer with hemosiderin, foreign body giant cells and lamina propria around the epithelium
Microscopic (histologic) images

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Mucin filled cysts (PAS diastase)