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Small bowel (small intestine)

Inflammatory disorders

Enterocolic (lymphocytic) phlebitis

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 15 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

Clinical features

● Venous lesions with lymphocytic infiltration of venular wall, necrotizing phelibitis, granulomatous phlebitis and endothelial and myointimal hyperplasia (Am J Surg Pathol 2000;24:824, Arch Pathol Med Lab 2007;131:1130)
● Also called lymphocytic or granulomatous or necrotizing phlebitis, myointimal venous hyperplasia
● Also ischemia and necrosis of ileum or colon due to localized phlebitis associated with fresh or organized thrombus of intramural mesenteric veins
● No systemic vasculitis
● Associated with hydroxyethyl rutozide, also other drugs
● Does not recur after surgery


● Predominantly lymphocytic infiltration of intramural tributaries of mesenteric veins

Case reports

● 53 year old man with coexisting lymphocytic colitis, lymphocytic enteritis, and lymphocytic appendicitis (Am J Surg Pathol 2004;28:542)
● 66 year old woman with isolated mesocolic vasculitis (Am J Surg Pathol 2001;25:827)
● 68 year old man with chronic antral ulcer associated with gastroduodenal lymphocytic phlebitis (Am J Surg Pathol 2004;28:1659)
● 74 year old woman with ischemic colitis (Mod Pathol 2000;13:897)

Micro description

● Lymphocytic infiltrate of venules

Micro images

End of Small bowel (small intestine) > Inflammatory disorders > Enterocolic (lymphocytic) phlebitis

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