Cite this page: Gulwani H. Enteroendocrine cell dysgenesis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelenteroendocrine.html. Accessed July 20th, 2019.
Definition / general
- Enteroendocrine cells are part of body's largest endocrine system; secrete multiple regulatory molecules which control physiological and homeostatic functions, particularly postprandial secretion and motility (Therap Adv Gastroenterol 2008;1:51)
- Enteroendocrine cell dysgenesis is extremely rare (1 known paper) congenital life threatening malabsorptive condition (Stanford University: Enteroendocrine Cell Dysgenesis [Accessed 23 February 2018])
- Defect is secondary to point mutations in NEUROG3, causing arrest of endocrine cell development in small intestine and colon (Hum Pathol 2007;38:570)