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Small bowel (small intestine)

Inflammatory disorders

Eosinophilic enteritis / gastroenteritis


Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 15 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Rare disease that may present as obstruction, associated with peripheral eosinophilia and allergic symptoms in children or young adults (Rev Esp Enferm Dig 2004;96:279, Ann Acad Med Singapore 2011;40:379, Ital J Pediatr 2011;37:18)
● Nausea, vomiting, diarrhea, steatorrhea, protein-losing enteropathy
● Symptoms are related to site of infiltration: mucosa of stomach/small bowel-diarrhea and malabsorption; submucosa and muscularis propria-obstruction; subserosa-ascites

Micro description
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● Marked eosinophilic infiltration of bowel wall (>20 eosinophils/HPF in at least one focus), prominent vessels, occasionally necrotizing granulomas and vasculitis
● Eosinophils typically not associated with other inflammatory cells
● Infiltration may be patchy

Micro images
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Various images

Differential diagnosis
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Ancylostoma caninum infection
● Collagen vascular disease
● Inflammatory bowel disease
● Lymphoma
● Sarcocystis infection

End of Small bowel (small intestine) > Inflammatory disorders > Eosinophilic enteritis / gastroenteritis


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