Small bowel (small intestine)
Other malignancies
Follicular dendritic cell sarcoma

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 23 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Follicular dendritic cell sarcoma small bowel

Cite this page: Gulwani, H. Follicular dendritic cell sarcoma. website. Accessed October 19th, 2018.
Definition / general
  • Rare tumor, first described in 1986 (Am J Pathol 1986;122:562)
  • Usually presents as painless, indolent mass (occasionally pain but without constitutional symptoms)
  • May be associated with Castleman disease - hyaline vascular type
  • Need immunostains for diagnosis
  • Usually lymph nodes, predominantly cervical, axillary or mediastinal (Am J Hematol 1998;59:161)
  • Extranodal sites include oral cavity, spleen, liver, small intestine, pancreas, peritoneum, soft tissue, skin
Poor prognostic factors
  • Large tumor size (6 cm or more), intraabdominal location and coagulative necrosis (Cancer 1997;79:294)
Case reports
  • Excision; often recurs locally, occasional distant metastases to liver or lung
Gross images

Images hosted on PathOut server:

Duodenal mass 10.5 x 10 cm

Microscopic (histologic) description
  • Storiform arrangement of oval or spindled cells, lymphocytic infiltrate
Microscopic (histologic) images

Images hosted on PathOut server:

Various images


Positive stains