Small bowel (small intestine)
Congenital anomalies
Heterotopic gastric mucosa

Author: Hanni Gulwani, M.D.

Revised: 10 May 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Heterotopic gastric mucosa small bowel[TIAB]

Cite this page: Gulwani, H. Heterotopic gastric mucosa. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelheterotopicgastric.html. Accessed July 22nd, 2018.
Definition / general
  • Mature gastric tissue in location where normally not found (i.e. small bowel)
  • Discrete small nodules or sessile polyps, usually in duodenum (first and second part)
  • May cause obstruction, diarrhea, ulceration, bleeding, perforation, intussusception, pain (Pediatr Dev Pathol 2000;3:277)
Case reports
Gross images

Images hosted on PathOut server:

Case of the Week #124:

Various images



Images hosted on other servers:

Figure 1

Microscopic (histologic) description
  • Mature gastric tissue, usually fundic type mucosa with chief and parietal cells, lined by foveolar epithelium, with a full mucosal thickness, forming a mucosal island
  • Divided into two subtypes, one lined by foveolar epithelium only (congenital or acquired) and another foveolar epithelium along with fundic glands (congenital only) (Int J Clin Exp Pathol 2012;5:46)
  • Gastric metaplasia in the duodenum is associated with H. pylori infection and is probably not congenital (Hum Pathol 2003;34:156)
Microscopic (histologic) images

Images hosted on PathOut server:

Contributed by
Andrey Bychkov, M.D., Ph.D.

Fundic mucosa in duodenum

 


Case of the Week #124:

Various images



Images hosted on other servers:

Various images

Differential diagnosis