Small bowel (small intestine) - Hyperplastic Pacinian corpuscle

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Small bowel (small intestine)

Benign tumors and tumor-like conditions

Hyperplastic Pacinian corpuscle

Reviewer: Hanni Gulwani, M.D. (see Reviewers page)
Revised: 20 December 2012, last major update August 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
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● Intraabdominal Pacinian corpuscles up to 1 cm

Micro description
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● Resembles cutaneous counterpart
● Central blood vessel and nerve ending surrounded by 14-45 tortuous, concentric lamellae

Micro images
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Digital lesion: A-relationship between pacinian corpuscle (P) and nerves (arrows); these two structures are interspersed with vascular and nervous twigs (double arrowheads) with surrounding loose connective and fatty tissues; B-normal structures of pacinian corpuscle are seen (outer capsule continuous with perineurium, lamellated inner and outer core, nerve fibers terminating center of inner core)

Digital lesion following dog bite: a-diffuse swelling; b-Pacinian hyperplasia with inner nerve fiber surrounded by concentric fibrous lamellae; c-inner core cells are S100+; d-outer lamellae are vimentin+; e-outer core cells are EMA+

Differential diagnosis
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● Strongyloides: has cuticle, internal structures

End of Small bowel (small intestine) > Benign tumors and tumor-like conditions > Hyperplastic Pacinian corpuscle

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