Small bowel (small intestine)
Benign tumors and tumor-like conditions
Hyperplastic pacinian corpuscle

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 19 February 2018, last major update August 2012

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Hyperplastic pacinian corpuscle

Cite this page: Gulwani, H. Hyperplastic pacinian corpuscle. website. Accessed March 21st, 2018.
Definition / general
  • Intraabdominal pacinian corpuscles up to 1 cm
Microscopic (histologic) description
  • Resembles cutaneous counterpart
  • Central blood vessel and nerve ending surrounded by 14 - 45 tortuous, concentric lamellae
Microscopic (histologic) images

Images hosted on other servers:

Digital lesion: (A) relationship between pacinian corpuscle (P) and nerves (arrows); these two structures
are interspersed with vascular and nervous twigs (double arrowheads) with surrounding loose connective
and fatty tissues; (B) normal structures of pacinian corpuscle are seen (outer capsule continuous with
perineurium, lamellated inner and outer core, nerve fibers terminating center of inner core)

Digital lesion following dog bite: (a) diffuse swelling;
(b) pacinian hyperplasia with inner nerve fiber surrounded
by concentric fibrous lamellae; (c) inner core cells are S100+;
(d) outer lamellae are vimentin+; (e) outer core cells are EMA+

Differential diagnosis