Small bowel (small intestine)
Benign tumors and tumor-like conditions
Inflammatory fibroid polyp

Author: Hanni Gulwani, M.D. (see Authors page)

Revised: 19 February 2018, last major update August 2012

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Inflammatory fibroid polyp small bowel

Cite this page: Gulwani, H. Inflammatory fibroid polyp. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/smallbowelinflammatoryfibroidpolyp.html. Accessed June 18th, 2018.
Definition / general
Case reports
Treatment
  • Excision (does not recur)
Gross description
  • Polypoid (without stalk), submucosal mass, dumbbell shape in small intestine due to intussuception, mucosal ulceration and splitting and atrophy of muscularis propria
Gross images

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Case of the Week #86:



Images hosted on other servers:

Inflammatory fibroid polyp

Microscopic (histologic) description
  • Submucosal mixture of prominent capillaries, spindle cells (occasionally concentrically arranged around vessels / onion skinning) and inflammatory cells (particularly eosinophils, plasma cells and mast cells) in granulation tissue-like stroma (Arch Pathol Lab Med 2010;134:378)
  • May be transmural
  • May have lymphoid follicles
  • Rare multinucleated giant cells, no atypia, no / rare mitotic figures
  • Histologic patterns: classical, edematous, fibrovascular, nodular, sclerotic
Microscopic (histologic) images

Images hosted on PathOut server:

Case of the Week #86:



Images hosted on other servers:

Various images

Positive stains
Negative stains
  • CD117 (although mast cells are positive)
Differential diagnosis